First evidence to show the toplogical change of DNAfrom B-DNA to Z-DNA Essay

First evidence to show the toplogical change of DNAfrom B-DNA to Z-DNA conformation in the hippocampus of Alzheimer's Brain - Essay Example The article claims that, there has been a discovery of altered DNA conformation for individuals suffering from AD (Suran et al 1). It is worthwhile giving credit to the article for clarity of objective. It has been able to differentiate and explain the differences in DNA configuration and conformation for both cases as well as providing evidence for intermediate cases. Additionally, the article was elaborate and illustrative enough whilst sticking to the objectives at the same time. For instance, the article explained the processes, which were used to come up with the evidence of B-DNA to Z-DNA conformation. On the other hand, the article may have failed to answer one important question. Truly, conformation happens but why. It only highlights the cause of disorders as degeneration of genetic material but does not go into elaborate detail on the process of degeneration. It can also be claimed that the article was overwhelmingly technical for persons outside the realms of medicine to understand anything. However, the main objective of the article was delivered in a scientifically acceptable

Independent Music Labels and Their impact on theMusic Industry Essay

Independent Music Labels and Their impact on theMusic Industry - Essay Example In recent times – fortunately or unfortunately we don’t know whether to call it a boon or a bane, there has been a sudden splurge of new private music companies which have given the existing scenario a total make-over by branding themselves on a different plane altogether. Besides the four major recording companies –i.e. Warner, Universal, Sony BMG and EMI, there are what are called â€Å"Indie† labels. The most common or widely used description of â€Å"independent† labels is that they are not connected with any major or corporate label. Such labels give more freedom and control, than what is allowed by major labels. They also extend support on the business aspect of music, though not on a very large scale. Independent labels face a downside in the fact that they lack the finance needed to make an artist or album popular. They are not capable of good advertisements or promotions for artists or albums. Most of these small labels are run by musicians from their home or garage. If it becomes a success, eventually it is taken over by a major label. The current scenario is pretty clear, both consumers and artists have spectacular opportunities from digital download technologies, as long as the artists are fairly compensated and major labels don’t interfere with it. Obviously, technology is changing the face of the Music industry.